Autism may be linked to antidepressant use

July 6th, 2011 by | Permalink

Antidepressants a cause of autism?

A study released Monday found mothers of children with autism were more likely to have been prescribed an antidepressant before birth than mothers of healthy children. Mothers who took the drug in the first trimester of pregnancy were three times more likely to have an autistic child.

Autism affects one out of every 150 children born in the United States and refers to a range of disorders from severe (such as an inability to communicate and mental retardation) to relatively mild symptoms (such as with Asperger’s syndrome).

Lisa Croen, director of the Autism Research Program at the Kaiser Permanente Division of Research in Oakland, California, led a team that conducted the study to see whether antidepressants known as selective serotonin reuptake inhibitors(SSRIs) contributed to autism risk. The study included nearly 300 children with autism and 1,500 randomly selected children and and included checking the medical records of their mothers.

Findings indicated that mothers of autistic children were twice as likely to have taken an antidepressant in the year before delivery than mothers in the control group. The trait was three times more common when antidepressants were taken in the first trimester of pregnancy.

Croen’s stated “Our results suggest a possible, albeit small, risk to the unborn child associated with in utero exposure to SSRIs,” but she cautioned that the risk must be balanced with the risk to the mother of having untreated depression. The SSRI study was preliminary and much more work is needed to understand the link between antidepressants and autism, according to the team.

Dr. Thomas Insel, director of the National Institute of Mental Health, commented “A threefold increase in risk is not insignificant. It is worth taking that into account with other factors.” 

Source: MSNBC.MSN.com

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  • Becky

    Both of my boys have autism 14 and 12 years old. I had my first when I was 18 yrs old, I did not take any antidepressants. There was two other articles if you have your child at an older age or if you smoke you are most likely to have an autistic child, none of these apply to me.

  • Roger Caldwell

    Yes, there are a lot of factors that can contribute to autism and some are genetic (and so completely beyond the control of the parent). I’m sorry I didn’t point that out more clearly in the article. There have actually been a few other studies done that you might be reading about soon that point out other environmental factors, as well. There is a great effort underway to understand this condition and I’m hoping it leads not only to prevention but also to a better understanding of the condition itself so that as a society we can better help those who have it.

  • Katherine Allen

    My son, Bradyn is 7 years old and has Autism. Bradyn doesnt talk (YET) and still in diapers. I have a lot of anxiety and fears about Bradyn talking and getting out of diapers and of course his future. When Bradyn was a baby around 6 months old I treated my daughter Tori who was 12 years old at the time for scabies with this very very very strong product called Lindane and on the bottle of Lindane it says to make sure you open your windows and doors for good ventalation. I truly think that my son Bradyn inhaled or breathed to much of the Lindane in because he had a strange reaction after I applied Lindane to my daughter. Bradyn all of a suddden , I thought he stopped breathing and had a blank stare and was not responding to anything. I freaked out and called the ambulance and Bradyn finally came out of that about an hour later but he wasnt the same after that. Of course at that time I had no clue about his Autism and he wasnt diagnosed until he was 3 years old and the experts keep saying that its part genetic and enviromental, well I believe the Lindane was so toxic for his little brain that it somehow caused Autism. If anyone has any information on this please email me at katthecleaner@rocketmail.com and thanks.
    Katherine Allen

  • Roger Caldwell

    Here’s one interesting article I stumbled on about Lindane and autism:

    http://health.groups.yahoo.com/group/ParentsAgainstLindane/message/24